PREV 711 GENETIC EPIDEMIOLOGY
This course provides the student with an overview of basic methods in genetic epidemiology, with application to common complex diseases such as coronary heart disease, type-2 diabetes and obesity. The course will begin with a review of basic human genetics and then proceed to a description of methods used to dissect the genetic contribution to human disease and to map genes. Topics include: assessment of familial aggregation, heritability analysis, segregation and linkage analysis, genetic association studies, and linkage dis-equilibrium mapping. The course will involve a computer lab, and students are expected to complete a data analysis project using genetic analysis software and to write up their results as a course project. Prerequisites: PREV 600, PREV 619, PREV 620 or their equivalents, or consent of instructor. Background in basic human genetics helpful.